Significant difference in gut microbiota Bifidobacterium species but not Lactobacillus species in colorectal cancer patients in comparison with healthy volunteers using quantitative real-time PCR
As a putative gut probiotic, depletion of bifidobacteria showed significant correlation to the development and progression of CRC; therefore, therapeutic use of these probiotic bacteria could be considered a possible adjuvant approach in disease management through modulation of the microbiota.
Authors
- Elahe Derakhshan-Nezhad
- Forough Alborzi
- Tayebe Shahbazi (ORCID: https://orcid.org/0000-0003-1212-8493)
- Bita Bakhshi (ORCID: https://orcid.org/0000-0002-7523-7905)
- Mahboube Bahroudi
- Mohammad Sadegh Fazeli (ORCID: https://orcid.org/0000-0002-2551-5890)
- Behnam Behboudi (ORCID: https://orcid.org/0000-0003-0632-7090)
- Mina Boustanshenas (ORCID: https://orcid.org/0000-0002-5447-9403)
- F. Esfandiari
- Sara Minaeeian
Institutions
- Tarbiat Modares University (IR)
- Iran University of Medical Sciences (IR)
- Mashhad University of Medical Sciences (IR)
- Imam Khomeini Hospital (IR)
- Tehran University of Medical Sciences (IR)
Publication Details
- Journal
- PLoS ONE
- Published
- 2024-11-27
- DOI
- https://doi.org/10.1371/journal.pone.0294053
- Citations
- 3
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.70
Funders
- Iran University of Medical Sciences
- Tarbiat Modares University