Burden and risk factors of suspected cholangiocarcinoma in high Opisthorchis viverrini endemic rural communities in southern Lao PDR
Our CCA screening in high OV prevalence rural areas of Lao PDR uncovers a high public health burden, primarily driven by elevated OV infection rates. Urgent interventions are needed to curb OV infection in these communities. Age and gender disparities in suspected CCA prevalence highlight the need for targeted efforts. Beyond OV, notable factors like a history of cholecystectomy offer valuable insights for preventive strategies. This research enhances our understanding of hepatobiliary morbidity and informs public health initiatives in Lao PDR.
Authors
- Phonesavanh Southisavath
- Jan Hattendorf (ORCID: https://orcid.org/0000-0002-1176-401X)
- Nicole M Probst-Hensch (ORCID: https://orcid.org/0000-0001-8561-5976)
- Kerstin Kling (ORCID: https://orcid.org/0000-0003-0223-0814)
- Savina Vorasane (ORCID: https://orcid.org/0000-0002-7395-832X)
- Anousin Homsana (ORCID: https://orcid.org/0009-0007-4804-1978)
- Somphou Sayasone (ORCID: https://orcid.org/0000-0001-8219-9567)
- Peter Odermatt (ORCID: https://orcid.org/0000-0002-0296-2508)
- Daniel H. Paris (ORCID: https://orcid.org/0000-0003-4743-5987)
Institutions
- Swiss Tropical and Public Health Institute (CH)
- University of Basel (CH)
- Robert Koch Institute (DE)
- Mahosot Hospital (LA)
- Public Health Institute (US)
Publication Details
- Journal
- PLoS neglected tropical diseases
- Published
- 2024-11-27
- DOI
- https://doi.org/10.1371/journal.pntd.0012617
- Citations
- 3
- Primary Topic
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.72
Funders
- National Science Foundation
- Freiwillige Akademische Gesellschaft
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
- Direktion für Entwicklung und Zusammenarbeit