Applications of marine microbial community models in the nature-based economy

Marine microorganisms are central to global ecological and biogeochemical systems, with their intricate interactions shaping community dynamics. While meta-omics data sets have revolutionized marine microbial ecology, they often provide fragmented insights, underscoring the need for advanced integrative modeling frameworks. In this review, we highlight the potential that community genome-scale metabolic models (cGEMs), in combination with meta-omics and environmental data sets, offer in advancing marine microbial ecology. We explore 3 key applications: quantifying marine ecosystem services, guiding bioremediation strategies for environmental challenges, and enhancing climate and biogeochemical models. Furthermore, we propose novel indices derived from cGEMs to assess microbial contributions to ecosystem functions, potentially informing economic valuation strategies for marine conservation. This interdisciplinary approach paves the way for innovative strategies in biotechnology, environmental restoration, and the development of nature-aligned economic systems, ultimately contributing to the preservation and sustainable use of marine ecosystems.