Lead-it-EAZY! GMP-compliant production of [212Pb]Pb-PSC-PEG2-TOC
The Lead-it-EAZY process performed stable and robust over ten radiosyntheses and yielded sterile [<sup>212</sup>Pb]Pb-VMT-α-NET in high purity for patient application. By changing the precursor this process could easily be adapted to other <sup>212</sup>Pb-radiopharmaceuticals.
Authors
- David Kästner (ORCID: https://orcid.org/0009-0003-6004-8639)
- Michael K. Schultz (ORCID: https://orcid.org/0000-0002-4554-2212)
- F. Kunkel
- Edwin A. Sagastume (ORCID: https://orcid.org/0000-0002-5911-0381)
- Enrico Michler (ORCID: https://orcid.org/0000-0002-4404-0114)
- Marc Pretze (ORCID: https://orcid.org/0000-0002-6432-5694)
- Jörg Kotzerke
Institutions
- University of Iowa (US)
- University Hospital Carl Gustav Carus (DE)
Publication Details
- Journal
- EJNMMI Radiopharmacy and Chemistry
- Published
- 2024-11-27
- DOI
- https://doi.org/10.1186/s41181-024-00305-8
- Citations
- 5
- Primary Topic
- Radiopharmaceutical Chemistry and Applications
- Type
- article
- Field-Weighted Citation Impact
- 2.02
Funders
- Technische Universität Dresden