Thermoeconomic Evaluation of the Triple Pressure-Swing Distillation Process

Objective: Investigate distillation as a separation process based on the difference in volatility of components, focusing on the separation of azeotropic mixtures using Pressure-Swing Distillation (PSD). The study was applied to the ternary mixture water-acetonitrile-isopropanol (Water-ACN-IPA). Theoretical Framework: Based on previous studies that demonstrated the feasibility of PSD for separating this mixture using three columns operating at different pressures. However, challenges related to high energy consumption persist due to system irreversibilities. Method: Hydraulic analysis of the columns is proposed, including the implementation of variable diameter and thermal integration as optimization strategies. Results and Discussion: Results show a 47.5% reduction in the total annual cost (TAC), demonstrating greater economic efficiency and process viability. Research Implications: The study contributes to improving energy efficiency in azeotropic separation processes using PSD, providing practical solutions to minimize costs and environmental impacts. Originality/Value: This work introduces technical innovations in azeotropic distillation using PSD, offering an economically optimized and viable approach for the chemical, petrochemical, and pharmaceutical industries.