Nivolumab plus Ipilimumab in Microsatellite-Instability–High Metastatic Colorectal Cancer
Progression-free survival was longer with nivolumab plus ipilimumab than with chemotherapy among patients who had not previously received systemic treatment for MSI-H or dMMR metastatic colorectal cancer. (Funded by Bristol Myers Squibb and Ono Pharmaceutical; CheckMate 8HW ClinicalTrials.gov number, NCT04008030.).
Authors
- Laëtitia Dahan (ORCID: https://orcid.org/0000-0001-5267-6190)
- Eray Goekkurt
- Ming Lei (ORCID: https://orcid.org/0000-0002-3962-6604)
- Tian Chen (ORCID: https://orcid.org/0009-0000-1023-1839)
- Michael Schenker (ORCID: https://orcid.org/0000-0003-2645-6391)
- Jaafar Bennouna (ORCID: https://orcid.org/0000-0002-5034-1108)
- María Luisa Limón (ORCID: https://orcid.org/0000-0003-4409-3029)
- Guillermo Méndez (ORCID: https://orcid.org/0000-0003-4675-6498)
- Lars Henrik Jensen (ORCID: https://orcid.org/0000-0002-0020-1537)
- Elvis Cela
- Heinz‐Josef Lenz (ORCID: https://orcid.org/0000-0003-2178-9568)
- Timuçin Çil (ORCID: https://orcid.org/0000-0002-5033-1479)
- Rocio García‐Carbonero (ORCID: https://orcid.org/0000-0002-3342-397X)
- Giampaolo Tortora (ORCID: https://orcid.org/0000-0002-1378-4962)
- Sara Lonardi (ORCID: https://orcid.org/0000-0002-7593-8138)
- Myriam Chalabi (ORCID: https://orcid.org/0000-0002-8607-6174)
- Christelle de la Fouchardière (ORCID: https://orcid.org/0000-0003-2291-5693)
- Takayuki Yoshino (ORCID: https://orcid.org/0000-0002-0489-4756)
- Maria Ignez Braghiroli (ORCID: https://orcid.org/0000-0001-6366-8786)
- Thierry André (ORCID: https://orcid.org/0000-0002-5103-7095)
- Eric Van Cutsem (ORCID: https://orcid.org/0000-0002-6372-1230)
- Jin Li (ORCID: https://orcid.org/0000-0001-9201-2321)
- Matthew Dixon (ORCID: https://orcid.org/0000-0002-4545-0799)
- Rohit Joshi (ORCID: https://orcid.org/0000-0003-4607-3937)
- Elena Élez
- Sandzhar Abdullaev
- José Luis Manzano Mozo
Institutions
- Sorbonne Université (FR)
- Hôpital Saint-Antoine (FR)
Publication Details
- Journal
- New England Journal of Medicine
- Published
- 2024-11-27
- DOI
- https://doi.org/10.1056/nejmoa2402141
- Citations
- 170
- Primary Topic
- Colorectal Cancer Treatments and Studies
- Type
- article
- Field-Weighted Citation Impact
- 48.03
Funders
- Bristol-Myers Squibb