Twice-Yearly Lenacapavir for HIV Prevention in Men and Gender-Diverse Persons

The HIV incidence with twice-yearly lenacapavir was significantly lower than the background incidence and the incidence with F/TDF. (Funded by Gilead Sciences; PURPOSE 2 ClinicalTrials.gov number, NCT04925752.).

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Publication Details

Journal
New England Journal of Medicine
Published
2024-11-27
DOI
https://doi.org/10.1056/nejmoa2411858
Citations
181
Primary Topic
HIV/AIDS Research and Interventions
Type
article
Field-Weighted Citation Impact
70.41

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article

Twice-Yearly Lenacapavir for HIV Prevention in Men and Gender-Diverse Persons

Jorge A. Gallardo-Cartagena, Marcus Lacerda, Lillian B. Brown, Carlos Roberto Brites et al.
181 citations
New England Journal of Medicine
HIV/AIDS Research and Interventions
70.41
article

Twice-Yearly Lenacapavir for HIV Prevention in Men and Gender-Diverse Persons

Jorge A. Gallardo-Cartagena, Marcus Lacerda, Lillian B. Brown, Carlos Roberto Brites, Onyema Ogbuagu, Anthony LaMarca, Shawn Hassler, Olivia T. Van Gerwen, Ramin Ebrahimi, Meredith E. Clement, Karam Mounzer, Richard Novák, Ricardo Vasconcelos, Susanne Doblecki‐Lewis, Valeria D Cantos, Paul Benson, Kenneth Hugh Mayer, Beatriz Grinsztejn, Tanya Schreibman, Anchalee Avihingsanon, Catherine Creticos, Jill S. Blumenthal, Allison L. Agwu, Aditya H. Gaur, Nittaya Phanuphak, Anthony Mills, Theo Hodge, Pedro Cahn, Pamela Wong, Jesse L. Clark, Jared M. Baeten, Breno Santos, Moti N. Ramgopal, J Vasquez, Christoph C Carter, Renu Singh, Moupali Das, LaShonda Spencer, Ricardo Sobhie Diaz, Marcelo Losso, Colleen F. Kelley, Stephanie Cox, Peter Ruane, Gordon Crofoot, Zwelethu Zwane, Jorge Sánchez, Nkosiphile Ndlovu, José Valdez Madruga, Chris Deaton, Juan Hinojosa, Cynthia Brinson, Richard Kaplan, Alma Perez Rios, Maribel Acevedo-Quiñones, Patric Schine
article en
181 citations

Abstract

The HIV incidence with twice-yearly lenacapavir was significantly lower than the background incidence and the incidence with F/TDF. (Funded by Gilead Sciences; PURPOSE 2 ClinicalTrials.gov number, NCT04925752.).

New England Journal of MedicineVol. 392(13)
Howard Brown Health Center (US), St. Jude Children's Research Hospital (US), Department of Natural and Environmental Resources (PR), Desmond Tutu HIV Foundation (ZA), Johns Hopkins University (US), University of Miami (US), Midway University (US), University of California, Los Angeles (US), Chicago Department of Public Health (US), National University of San Marcos (PE), University of the Witwatersrand (ZA), Universidad de Guadalajara (MX), Johns Hopkins Medicine (US), AIDS Clinical Trials Group (US), University of Alabama at Birmingham (US), Yale University (US), University of California San Diego (US), University of Illinois Chicago (US), Fundação de Medicina Tropical (BR), Complexo Hospitalar Universitário Professor Edgard Santos (BR), Grady Health System (US), Desert AIDS Project (US), Asociación para la Conservación de la Cuenca Amazónica (PE), Sarah Cannon (US), Hospital Ramos Mejía (AR), Clinical Research Organization (BD), Fundación Huésped (AR), Gilead Sciences (United Kingdom) (GB), Via Libre (PE), University of California San Francisco Medical Center (US), Oncotherapeutics (United States) (US), HOPE Clinic (US), Centro de Referência em Informação Ambiental (BR), HIV Netherlands Australia Thailand Research Collaboration (TH), Hospital Nossa Senhora da Conceição (BR), Aurum Institute (ZA), University of Illinois Hospital & Health Sciences System (US), Gilead Sciences (United States) (US), Instituto Evandro Chagas (BR), Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (BR), Ruane Medical (US), Therafirst Medical Center (US), Fenway Health (US), Fundação Oswaldo Cruz (BR), Charles R. Drew University of Medicine and Science (US), Louisiana State University Health Sciences Center New Orleans (US), Philadelphia Fight (US), Universidade Federal de São Paulo (BR)
Gilead Sciences
Gender equality
Openalex Percentile: Top 0%
HIV/AIDS Research and Interventions
70.41
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