KLF14 inhibits tumor progression via FOSL1 in glioma
This study highlights that FOSL1 is negatively regulated by KLF14 in glioblastoma and suggests that KLF14 overexpression can mitigate tumor growth by inhibiting FOSL1, thus identifying KLF14 as a novel molecular target for treating glioblastoma. Further research into the interplay and regulatory dynamics between KLF14 and FOSL1 under varying stress conditions can enhance the precision of glioblastoma treatment.
Authors
- Xuelai Liu
- Yongfang Yang (ORCID: https://orcid.org/0000-0003-1033-8737)
- Xinjuan Qu
- Guangjian Fan (ORCID: https://orcid.org/0000-0003-0684-1380)
- Yuanyuan Zeng (ORCID: https://orcid.org/0000-0002-2260-4468)
- Hongwei Chen (ORCID: https://orcid.org/0000-0002-9400-6053)
- Xiaohua Wang (ORCID: https://orcid.org/0000-0002-3050-6577)
- Zhenguo Wang (ORCID: https://orcid.org/0000-0002-3158-2002)
- Yujuan Zhang (ORCID: https://orcid.org/0000-0002-2845-2960)
- Kaiyue Wang (ORCID: https://orcid.org/0000-0002-3218-7151)
- Yuming Li (ORCID: https://orcid.org/0000-0002-9948-5110)
- Ting Zhu (ORCID: https://orcid.org/0000-0002-0741-0489)
Institutions
- Guangzhou University of Chinese Medicine (CN)
- Shanghai Jiao Tong University (CN)
- Linyi People's Hospital (CN)
- Tongren Hospital (CN)
- Linyi City Chinese Medicine Hospital (CN)
- Songjiang District Central Hospital (CN)
- Shanghai Clinical Research Center (CN)
Publication Details
- Journal
- Biochemistry and Biophysics Reports
- Published
- 2024-11-27
- DOI
- https://doi.org/10.1016/j.bbrep.2024.101885
- Citations
- 2
- Primary Topic
- Kruppel-like factors research
- Type
- article
- Field-Weighted Citation Impact
- 0.47