Systemic immune-inflammatory index predicts fragility fracture risk in postmenopausal anemic females with type 2 diabetes mellitus: evidence from a longitudinal cohort study
The SII revealed a significant positive association with a real-world fragility fracture event and a future 10-year fragility fracture probability in postmenopausal females with T2DM, particularly evident in individuals with anemia. Therefore, monitoring the SII and hemoglobin in postmenopausal older women with T2DM is helpful in routine clinical practice to identify individuals at high risk for fragility fractures and to promptly execute appropriate fracture intervention procedures.
Authors
- Wensheng Lu (ORCID: https://orcid.org/0000-0002-0212-3624)
- Qi He (ORCID: https://orcid.org/0000-0001-5437-3169)
- Zhenwei Zhai
- Jingxia Sun
- Chiu‐Wing Winnie Chu (ORCID: https://orcid.org/0000-0003-4962-4132)
- Xiaoqin Qiu (ORCID: https://orcid.org/0000-0002-3809-4351)
- Jianhao Huang (ORCID: https://orcid.org/0000-0001-9973-8109)
- Jinming Yu (ORCID: https://orcid.org/0000-0001-7710-5466)
- Qiu Wang (ORCID: https://orcid.org/0000-0003-1635-8050)
- Jiangmei Pan
- Dinggui Huang
Institutions
- Health Commission of Anhui Province (CN)
- The People's Hospital of Guangxi Zhuang Autonomous Region (CN)
- First Affiliated Hospital of GuangXi Medical University (CN)
- Riverside Hospital of Guangxi Zhuang Autonomous Region (CN)
Publication Details
- Journal
- BMC Endocrine Disorders
- Published
- 2024-11-27
- DOI
- https://doi.org/10.1186/s12902-024-01792-1
- Citations
- 3
- Primary Topic
- Bone health and osteoporosis research
- Type
- article
- Field-Weighted Citation Impact
- 1.43
Funders
- Guangxi Key Research and Development Program