Prognostic Markers of Severity of Chronic Kidney Disease in Patients with Metabolic Associated Fatty Liver Disease

Background: One risk factor for the occurrence of an event is nonalcoholic fatty liver disease (NAFLD), and the severity of NAFLD can raise the risk of chronic kidney disease (CKD) even more. Objective: To assess the relationship between the severity of CKD and metabolic associated fatty liver disease (MAFLD) Patients and Methods: This cross-sectional study was carried out on 60 patients aged from 18 to 80 years old, of both sexes, diagnosed as MAFLD and CKD. All patients were subjected to serum triglyceride level, total, LDL and HDL cholesterol, FBG, serum creatinine, ALT, AST, GGT, eGFR, albuminuria, serum uric acid and ferritin measurements. Results: There was a significant negative correlation between eGFR and BMI, FBS, LDL, total cholesterol, serum ferritin, AST, ALT, albuminuria, S. creatinine and S. uric acid. There was no significant difference between eGFR with age, HDL, triglyceride, hemoglobin, total leukocytic count, and GGT. There was a significant difference among the grades for both livers, indicating variations in eGFR levels across the different grades in both organs. Conclusions: Regardless of conventional risk factors, MAFLD was linked to a greater frequency of CKD, and the incidence of CKD was positively correlated with the severity of MAFLD as determined by non-invasive techniques.