Efficacy of Antioxidant Therapy Using Quercetin Nano-emulgel as Adjuvant Local Delivery Drug in Non-surgical Treatment of Periodontitis Patients

Aim: This study designed to compare clinically and radiographically between Platelet Rich Fibrin (PRF) membrane and collagen membranes in combination with Beta tri calcium phosphate βTCP/collagen in treatment of dehiscence around immediately placed dental implant. Subjects and methods: This study was performed on 20 sites from 20 patients who each received an immediate implant for a single tooth replacement at a maxillary anterior or premolar site. Patients were divided into two groups according to the augmented materials used. One group received an immediate implant and filling of defects using Beta Tri Calcium Phosphate/Collagen bone graft covered with PRF membrane. The other group received an immediate implant and filling of defects with Beta Tri Calcium Phosphate/Collagen covered with collagen membrane. Cone beam computed tomography (CBCT) was taken before placement, and at 6 and 12 months post-surgery. Results: Both treatment procedures resulted in significant improvements for the primary outcome regarding bone fill as well as thickness and height of buccal bone. In addition, statistically significant differences were found in the buccal bone height, thickness and bone density for the group treated with Beta Tri Calcium Phosphate/Collagen combined with collagen membrane compared with sites treated with Beta Tri Calcium Phosphate/Collagen combined with PRF membrane .Conclusion: Beta Tri Calcium Phosphate/Collagen combined with collagen membrane is significantly superior than Beta Tri Calcium Phosphate/Collagen combined with PRF membrane in treatment of buccal bone dehiscence during immedite implant placement