Montelukast inhibits abdominal aortic aneurysm formation in mice via activating the AMPK/mTOR signalling pathway
Montelukast can inhibit AAA formation in mice, possibly through the downregulation of cell apoptosis, inflammatory response, and matrix metalloproteinase levels via the AMPK/mTOR signaling pathway.
Authors
- Jiamao Wang
- Jiawei Zhuang (ORCID: https://orcid.org/0000-0002-2240-3201)
- Zhonggui Shan
- Jian Huang (ORCID: https://orcid.org/0009-0006-0506-7783)
Institutions
- First Affiliated Hospital of Xiamen University (CN)
Publication Details
- Journal
- Langenbeck s Archives of Surgery
- Published
- 2024-11-27
- DOI
- https://doi.org/10.1007/s00423-024-03527-1
- Citations
- 3
- Primary Topic
- Aortic aneurysm repair treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.26