Identification of Cadmium (CD) metal binding sites in _Eudrilus eugeniae using Insilico protocols

The application of Eudrilus eugeniae earthworm species in bioremediation of contaminated soil results in a decrease in the concentration of pollutants by way of a mechanism known as bioaccumulation.Eudrilus eugeniae's body accumulation of cadmium metal is the subject of the current insilico study.The Cytochrome Oxidase 1 (COX1) protein of Eudrilus eugeniae accumulates cadmium metal.This study's technique includes molecular drug docking and H-bond interaction research using sophisticated automated drug docking platforms.The findings unequivocally demonstrate that Eudrilus eugeniae contains a significant amount of cysteine residues, which bind to a variety of heavy metals, most notably cadmium.Our findings align with the previously validated wet lab results as well.Ultimately, it was determined that cadmium metal directly binds to cysteine-rich amino acid locations.Based on the expression of the Cytochrome Oxidase 1 protein, these results have demonstrated that Eudrilus eugeniae is capable of collecting Chromium metal in its body.The complete Insilico study describes in detail how metals build up in a specific species of earthworm.

Authors

Publication Details

Journal
African Journal of Biomedical Research
Published
2024-11-23
DOI
https://doi.org/10.53555/ajbr.v27i4s.4058
Primary Topic
Analytical chemistry methods development
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Identification of Cadmium (CD) metal binding sites in _Eudrilus eugeniae using Insilico protocols

A Suvedha
African Journal of Biomedical Research
Analytical chemistry methods development
article

Identification of Cadmium (CD) metal binding sites in _Eudrilus eugeniae using Insilico protocols

A Suvedha
article en

Abstract

The application of Eudrilus eugeniae earthworm species in bioremediation of contaminated soil results in a decrease in the concentration of pollutants by way of a mechanism known as bioaccumulation.Eudrilus eugeniae's body accumulation of cadmium metal is the subject of the current insilico study.The Cytochrome Oxidase 1 (COX1) protein of Eudrilus eugeniae accumulates cadmium metal.This study's technique includes molecular drug docking and H-bond interaction research using sophisticated automated drug docking platforms.The findings unequivocally demonstrate that Eudrilus eugeniae contains a significant amount of cysteine residues, which bind to a variety of heavy metals, most notably cadmium.Our findings align with the previously validated wet lab results as well.Ultimately, it was determined that cadmium metal directly binds to cysteine-rich amino acid locations.Based on the expression of the Cytochrome Oxidase 1 protein, these results have demonstrated that Eudrilus eugeniae is capable of collecting Chromium metal in its body.The complete Insilico study describes in detail how metals build up in a specific species of earthworm.

African Journal of Biomedical Research
Openalex Percentile: Top 80%
Analytical chemistry methods development
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.