The circadian clock gene BMAL1 modulates autoimmunity features in lupus
<i>Bmal1</i> is associated with lower disease activity in SLE. These results indicate that perturbation in the circadian rhythm of neutrophils can have pathogenic consequences in SLE.
Authors
- Norio Hanata (ORCID: https://orcid.org/0000-0002-0195-4039)
- Mariana J. Kaplan (ORCID: https://orcid.org/0000-0003-2968-0815)
- Sarfaraz Hasni (ORCID: https://orcid.org/0000-0002-4164-8837)
- Donavon Sandoval-Heglund (ORCID: https://orcid.org/0000-0003-1979-005X)
- Zerai Manna (ORCID: https://orcid.org/0000-0003-1318-2213)
- Shuichiro Nakabo (ORCID: https://orcid.org/0000-0002-9250-1851)
- Elaine Poncio
- Mingzeng Zhang (ORCID: https://orcid.org/0000-0001-6875-8940)
- Stephen R. Brooks (ORCID: https://orcid.org/0000-0001-5592-5332)
- Stefania Dell’Orso (ORCID: https://orcid.org/0000-0002-1634-5631)
- William G Ambler (ORCID: https://orcid.org/0000-0003-0573-9173)
- Victoria Hoffmann
- Shamima Islam
Institutions
- National Institutes of Health (US)
- Office of Science (US)
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (US)
- Office of Research Services (US)
- Biota Pharmaceuticals (United States) (US)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-11-27
- DOI
- https://doi.org/10.3389/fimmu.2024.1465185
- Citations
- 6
- Primary Topic
- Circadian rhythm and melatonin
- Type
- article
- Field-Weighted Citation Impact
- 1.64
Funders
- National Institutes of Health
- Office of Science
- National Institute of Arthritis and Musculoskeletal and Skin Diseases