Is Aspirin Safe for Thromboprophylaxis After Surgery for Lower Extremity Neoplastic Pathologic Fractures?

Our study demonstrates that the administration of enoxaparin in patients undergoing surgical intervention for neoplastic pathologic fractures of the lower extremities may lead to significantly higher rates of aggregate VTE postoperatively compared to ASA. This data suggests that further research is warranted to determine if surgeons may safely consider using ASA in patients with no other reported risk factors or need for anticoagulation postoperatively, even in active malignancy.

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Publication Details

Journal
Journal of Surgical Oncology
Published
2024-11-26
DOI
https://doi.org/10.1002/jso.27997
Citations
1
Primary Topic
Venous Thromboembolism Diagnosis and Management
Type
article
Field-Weighted Citation Impact
0.55
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article

Is Aspirin Safe for Thromboprophylaxis After Surgery for Lower Extremity Neoplastic Pathologic Fractures?

Brandon S. Gettleman, Matthew S. Chen, Mary K. Richardson, Kevin C. Liu et al.
1 citations
Journal of Surgical Oncology
Venous Thromboembolism Diagnosis and Management
0.55
article

Is Aspirin Safe for Thromboprophylaxis After Surgery for Lower Extremity Neoplastic Pathologic Fractures?

Brandon S. Gettleman, Matthew S. Chen, Mary K. Richardson, Kevin C. Liu, Alexander B. Christ, Lawrence R. Menendez, Nathanael D. Heckmann, Arad Talehakimi
article en
1 citations

Abstract

Our study demonstrates that the administration of enoxaparin in patients undergoing surgical intervention for neoplastic pathologic fractures of the lower extremities may lead to significantly higher rates of aggregate VTE postoperatively compared to ASA. This data suggests that further research is warranted to determine if surgeons may safely consider using ASA in patients with no other reported risk factors or need for anticoagulation postoperatively, even in active malignancy.

Journal of Surgical OncologyVol. 131(5)
University of South Carolina (US), Kansas City University (US), University of California, Los Angeles (US), Keck Hospital of USC (US), VA Greater Los Angeles Healthcare System (US)
Good health and well-being
Openalex Percentile: Top 29%
Venous Thromboembolism Diagnosis and Management
0.55
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Is Aspirin Safe for Thromboprophylaxis After Surgery for Lower Extremity Neoplastic Pathologic Fractures? — Brandon S. Gettleman, Matthew S. Chen, et al. · Journal of Surgical Oncology (2024) | TGRS Research Map | TGRS