Extracellular vesicles epitopes as potential biomarker candidates in patients with traumatic spinal cord injury
We identified four potential EV-based tSCI biomarkers (CD47+, CD56+, CD68+, and ADAM17+ EVs) that differ in tSCI, with CD47+ EVs showing a strong correlation with the neurological function in tSCI. Thus, future studies might further specify the relevance of potential tSCI-specific biomarkers and investigate underlying mechanisms of tSCI.
Authors
- Cora Rebecca Schindler (ORCID: https://orcid.org/0000-0002-3535-7216)
- İngo Marzi (ORCID: https://orcid.org/0000-0003-3677-2910)
- Marek Widera (ORCID: https://orcid.org/0000-0001-5417-9307)
- Liudmila Leppik (ORCID: https://orcid.org/0000-0003-0362-4727)
- Inna Schaible
- Christiane Pallas
- Dirk Henrich (ORCID: https://orcid.org/0000-0002-9728-4032)
- Birte Weber (ORCID: https://orcid.org/0009-0006-3354-0304)
- Jason-Alexander Hörauf
- André El Saman (ORCID: https://orcid.org/0000-0003-0002-5243)
- Min‐Hong Wang (ORCID: https://orcid.org/0000-0003-0394-1001)
Institutions
- Goethe University Frankfurt (DE)
- University Hospital Frankfurt (DE)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-11-27
- DOI
- https://doi.org/10.3389/fimmu.2024.1478786
- Citations
- 6
- Primary Topic
- Spinal Cord Injury Research
- Type
- article
- Field-Weighted Citation Impact
- 2.55
Funders
- Deutsche Forschungsgemeinschaft