Urolithin A and nicotinamide riboside differentially regulate innate immune defenses and metabolism in human microglial cells
These findings underscore the potential of UA and NR as therapeutic agents in managing neuroinflammation and mitochondrial dysfunction in neurodegenerative diseases.
Authors
- Cláudia Maria Navarro (ORCID: https://orcid.org/0000-0002-3185-2826)
- Deborah L. Croteau (ORCID: https://orcid.org/0000-0002-6094-4084)
- Helena Borland Madsen (ORCID: https://orcid.org/0009-0002-6351-2700)
- Vilhelm A. Bohr (ORCID: https://orcid.org/0000-0003-4823-6429)
- Jae Hyeon Park (ORCID: https://orcid.org/0000-0002-4217-1145)
- Zhiquan Li (ORCID: https://orcid.org/0000-0003-3253-7606)
- Emilie Gasparini
Institutions
- University of Copenhagen (DK)
- National Institute on Aging (US)
- Capital Region of Denmark (DK)
Publication Details
- Journal
- Frontiers in Aging Neuroscience
- Published
- 2024-11-27
- DOI
- https://doi.org/10.3389/fnagi.2024.1503336
- Citations
- 4
- Primary Topic
- Pomegranate: compositions and health benefits
- Type
- article
- Field-Weighted Citation Impact
- 1.24
Funders
- Novo Nordisk Fonden