Observation of the Efficacy of Different Administration Routes of Tranexamic Acid in the Treatment of Melasma

Facial hyperpigmentation, commonly known as melasma, primarily affects women of childbearing age. This condition has complex causes, including hormonal imbalances, genetic factors, UV exposure, oxidative stress, local microbial balance, cosmetic use, and psychological stress, all of which greatly impact patients’ appearance and mental well-being. Although current treatments for melasma yield limited results, research has indicated that oral tranexamic acid shows some clinical effectiveness in treating melasma. This study aims to explore the therapeutic effects of different administration methods of tranexamic acid on patients with melasma, with the goal of providing new insights for clinical treatment.