A case of sigmoid colon carcinoma presenting as pyrexia of unknown origin

Pyrexia of unknown origin (PUO) is a diagnostic challenge with a variety of causative factors, one of which is malignancy. This report throws light on sigmoid colon carcinoma, one of the lesser understood causes of pyrexia of unknown origin, where unremitting fever was the presenting symptom. Exclusion of common infectious causes of fever with thorough diagnostic work up lead to a diagnosis of adenocarcinoma of sigmoid colon. Fever subsided completely in the postoperative course.