Nonspecific increase of αβTCR+ double-negative T cells in pediatric rheumatic diseases
These preliminary results indicate that circulating αβ<sup>+</sup>DNT cells are significantly expanded in children with rheumatic disorders; however, this finding appears to be a nonspecific (disease-unrelated) marker of autoimmunity. Further and larger studies are necessary to better investigate and define the role of DNT cells in pediatric rheumatic diseases.
Authors
- Naanlep Matthew Tanko (ORCID: https://orcid.org/0000-0003-1270-1886)
- Lyudmila Akhmaltdinova (ORCID: https://orcid.org/0000-0001-5602-6136)
- Dimitri Poddighe (ORCID: https://orcid.org/0000-0001-6431-9334)
- Zaure Mukusheva (ORCID: https://orcid.org/0000-0002-9728-6206)
- Kuanysh Dossybayeva (ORCID: https://orcid.org/0000-0002-1834-1909)
- Gulsamal Zhubanova
- Assel Mussayeva
- Aiken Dildabayeva
- Galiya Nauryzbayeva
- Ulbolsyn Orumbayeva
Institutions
- Astana Medical University (KZ)
- VinUniversity (VN)
- National Research Center for Maternal and Child Health (KZ)
- Nazarbayev University (KZ)
Publication Details
- Journal
- World Journal of Pediatrics
- Published
- 2024-11-28
- DOI
- https://doi.org/10.1007/s12519-024-00854-7
- Citations
- 3
- Primary Topic
- Immune Cell Function and Interaction
- Type
- article
- Field-Weighted Citation Impact
- 0.72
Funders
- Ministry of Education and Science of the Republic of Kazakhstan
- Nazarbayev University