Urinary Dickkopf‐3 as a Potential Marker for Estimated Glomerular Filtration Rate Decline in Patients With Heart Failure
The present findings indicate that uDKK3 is a promising prognostic biomarker for subsequent eGFR decline in patients with HF, irrespective of the presence of chronic kidney disease and even in the early stages of HF. This potential allows for early intervention to mitigate the deterioration of kidney function. Further investigation is warranted to validate its clinical utility.
Authors
- Anja Sandek
- Hassan Dihazi (ORCID: https://orcid.org/0000-0003-3417-0385)
- Stephan Lüders (ORCID: https://orcid.org/0000-0003-3007-9015)
- Dennis Pieper
- Andreas Leha (ORCID: https://orcid.org/0000-0002-8072-1988)
- Michael Koziolek (ORCID: https://orcid.org/0000-0002-0897-5430)
- Ann‐Kathrin Schäfer (ORCID: https://orcid.org/0000-0003-2676-9670)
- Manuel Wallbach (ORCID: https://orcid.org/0000-0002-1162-4682)
- Michael Zeisberg (ORCID: https://orcid.org/0000-0001-5826-738X)
- Gry H. Dihazi (ORCID: https://orcid.org/0000-0002-3214-7969)
Institutions
- St. Josefs-Hospital Cloppenburg (DE)
- Universitätsmedizin Göttingen (DE)
- German Centre for Cardiovascular Research (DE)
- University of Göttingen (DE)
Publication Details
- Journal
- Journal of the American Heart Association
- Published
- 2024-11-27
- DOI
- https://doi.org/10.1161/jaha.124.036637
- Citations
- 4
- Primary Topic
- Dialysis and Renal Disease Management
- Type
- article
- Field-Weighted Citation Impact
- 1.36