Safety of alteplase intravenous thrombolysis and influencing factors of clinical outcome in elderly patients with acute ischemic stroke
Elderly AIS patients after rt-PA thrombolysis therapy can improve the short-term, long-term prognosis. The risk of intracranial hemorrhage transformation and death is not higher than that of elderly non thrombolytic patients, indicating that rt-PA treatment is safe for elderly AIS patients. The NIHSS score before treatment was an independent risk factor affecting the long-term prognosis of elderly AIS patients after thrombolytic therapy.
Authors
- Lifen Chi
- Hao Shu (ORCID: https://orcid.org/0009-0004-3628-2326)
- Yongyin Zhang
- Xiaoyi Song (ORCID: https://orcid.org/0000-0002-0299-151X)
- Shunkai Zhang (ORCID: https://orcid.org/0009-0006-5974-4313)
- Xuerong Huang (ORCID: https://orcid.org/0000-0001-5013-8698)
- Qiang Zhou (ORCID: https://orcid.org/0000-0001-9950-8311)
Institutions
- Wenzhou Medical University (CN)
- Ruian People's Hospital (CN)
Publication Details
- Journal
- BMC Neurology
- Published
- 2024-11-28
- DOI
- https://doi.org/10.1186/s12883-024-03973-w
- Citations
- 1
- Primary Topic
- Acute Ischemic Stroke Management
- Type
- article
- Field-Weighted Citation Impact
- 0.39