Genomics reveal local skin immune response key to control sarcoptic mange in Iberian ibex (Capra pyrenaica)
The results demonstrate that skin local cellular immune response is key to control sarcoptic mange and prevent the systemic spread of the disease and the associated inflammatory response. These results will be useful to understand the pathogenesis and drivers of the differential outcome of mange at individual scale, and the population and ecological consequences of such variability in Iberian ibex, as well as in other wildlife species, domestic animals, and humans.
Authors
- Jorge Ramón Lopez‐Olvera (ORCID: https://orcid.org/0000-0002-2999-3451)
- Emmanuel Serrano (ORCID: https://orcid.org/0000-0002-9799-9804)
- José Enrique Granados (ORCID: https://orcid.org/0000-0002-9787-9896)
- Eulàlia Puigdecanet (ORCID: https://orcid.org/0000-0001-6067-9332)
- Paulino Fandós (ORCID: https://orcid.org/0000-0002-9607-8931)
- Marta Bódalo‐Torruella (ORCID: https://orcid.org/0000-0002-5950-4700)
- Lara Nonell (ORCID: https://orcid.org/0000-0002-8538-8213)
- Arián Ráez‐Bravo (ORCID: https://orcid.org/0000-0002-3190-1659)
- Ramón C. Soriguer (ORCID: https://orcid.org/0000-0002-9165-7766)
- José Espinosa (ORCID: https://orcid.org/0000-0002-9036-1402)
- Francisco Javier Cano-Manuel
- Jesús M. Pérez (ORCID: https://orcid.org/0000-0001-9159-0365)
Institutions
- Universitat Autònoma de Barcelona (ES)
- Universidad de Jaén (ES)
- Sierra Nevada Corporation (United States) (US)
- Estación Biológica de Doñana (ES)
- Unidades Centrales Científico-Técnicas (ES)
- Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (ES)
- Hospital del Mar Research Institute (ES)
- Instituto de Ganadería de Montaña (ES)
- Universidad de León (ES)
Publication Details
- Journal
- BMC Genomics
- Published
- 2024-11-27
- DOI
- https://doi.org/10.1186/s12864-024-10999-4
- Citations
- 2
- Primary Topic
- Dermatological diseases and infestations
- Type
- article
- Field-Weighted Citation Impact
- 0.78
Funders
- Ministerio de Economía y Competitividad
- Junta de Andalucía