Clinical Analysis of Trastuzumab-Targeted and Chemotherapy Treatment for Breast Cancer Patients

Objective: To explore the clinical effectiveness and safety of trastuzumab combined with chemotherapy in breast cancer patients. Methods: Eighty patients with postoperative local recurrence of breast cancer were divided into a control group (chemotherapy only) and an observation group (chemotherapy plus trastuzumab-targeted therapy). The clinical efficacy, adverse reactions, and complications were compared between groups. Results: The overall effective rate of clinical treatment in the observation group was higher than that in the control group (P < 0.05). The incidence of adverse reactions showed no difference between the groups (P > 0.05), while the complication rate was significantly lower in the observation group (P < 0.05). Conclusion: Trastuzumab-targeted therapy combined with chemotherapy can significantly improve clinical treatment outcomes for breast cancer patients, reduce the risk of complications, and maintain good safety, making it suitable for clinical promotion.

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Publication Details

Journal
Proceedings of Anticancer Research
Published
2024-11-27
DOI
https://doi.org/10.26689/par.v8i6.8955
Primary Topic
HER2/EGFR in Cancer Research
Type
article
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article

Clinical Analysis of Trastuzumab-Targeted and Chemotherapy Treatment for Breast Cancer Patients

Ying Liang
Proceedings of Anticancer Research
HER2/EGFR in Cancer Research
article

Clinical Analysis of Trastuzumab-Targeted and Chemotherapy Treatment for Breast Cancer Patients

Ying Liang
article en

Abstract

Objective: To explore the clinical effectiveness and safety of trastuzumab combined with chemotherapy in breast cancer patients. Methods: Eighty patients with postoperative local recurrence of breast cancer were divided into a control group (chemotherapy only) and an observation group (chemotherapy plus trastuzumab-targeted therapy). The clinical efficacy, adverse reactions, and complications were compared between groups. Results: The overall effective rate of clinical treatment in the observation group was higher than that in the control group (P < 0.05). The incidence of adverse reactions showed no difference between the groups (P > 0.05), while the complication rate was significantly lower in the observation group (P < 0.05). Conclusion: Trastuzumab-targeted therapy combined with chemotherapy can significantly improve clinical treatment outcomes for breast cancer patients, reduce the risk of complications, and maintain good safety, making it suitable for clinical promotion.

Proceedings of Anticancer ResearchVol. 8(6)
Kunming Medical University (CN)
Good health and well-being
Openalex Percentile: Top 62%
HER2/EGFR in Cancer Research
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