Microneedling Radiofrequency for Acne Vulgaris in Adolescents as a Promising Device-Based Treatment: A Clinical Case Series

<b><i>Background:</i></b> Acne vulgaris is a persistent inflammatory condition affecting the sebaceous unit, in whose pathophysiology the Propionibacterium acnes (P. acnes) play an important role, and that can have major psychological effects. <b><i>Objective:</i></b> The current study aims to investigate the safety and efficacy of an innovative fractional microneedle radiofrequency (RFMN) device for acne management in adolescents. <b><i>Materials and Methods:</i></b> A total of 21 Caucasian young patients with facial acne of all grades of severity underwent three treatment sessions spaced 15/30 days apart with an RFMN device. The Acne Radar Questionnaire was administered to all patients. The data were represented using Radar graph, and the sample population was distributed in quartiles. The first quartile, the second quartile, and the third quartile were calculated for all patient populations before and at 6 months follow-up (6 MFU). The evaluation of the severity of acne lesions was assessed by using the Global Acne Severity scale. Photographs of patients with acne were acquired with a digital camera before and at 6 MFU after the last treatment session. <b><i>Results:</i></b> The mean values of each item of the Acne Radar Questionnaire significantly (<i>p</i> < 0.001) improved for all patients treated. The analyses obtained by the quartiles showed that all variables improved after the treatment with the study device. The photographic images confirm the positive results and the improvement of acne lesions. No major side effects were observed. <b><i>Conclusions:</i></b> The study system appears to be an effective and safe treatment choice for patients with inflammatory active acne and acne scarring.