Multi-omics analysis reveals indicator features of microbe-host interactions during Candida albicans colonization and subsequent infection
<i>Candida albicans</i> invasive infections pose a significant challenge to contemporary medicine, with mortality rates from such fungal infections remaining high despite antifungal treatment. Gastrointestinal colonization by potential pathogens is a critical precursor to the development of translocated infections. Consequently, there is an increasing demand to identify clinical risk factors, multi-omics profiles, and key indicators to prevent the progression to translocated invasive infections in patients colonized rectally by <i>C. albicans</i>.
Authors
- Hongchao Jiang (ORCID: https://orcid.org/0000-0002-8467-8446)
- Jianhua Gan (ORCID: https://orcid.org/0000-0002-8438-8852)
- Jiangkun Yu (ORCID: https://orcid.org/0000-0002-1832-7832)
- Huan Zhang (ORCID: https://orcid.org/0000-0002-2289-7707)
- Di Chen (ORCID: https://orcid.org/0009-0004-1791-2302)
- Zhi Zhang (ORCID: https://orcid.org/0000-0003-3258-1447)
- Hui Li (ORCID: https://orcid.org/0000-0001-6214-8308)
- Li Zhao (ORCID: https://orcid.org/0000-0001-6776-1996)
- Guangjuan Wu
- Qiulin Luo
- Wenli Yuan (ORCID: https://orcid.org/0000-0002-6396-1218)
- De‐Yao Deng
- Daoyuan Song
- Yingpu Wei
Institutions
- Yunnan University (CN)
- Kunming Children's Hospital (CN)
- Second People's Hospital of Yunnan Province (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2024-11-27
- DOI
- https://doi.org/10.3389/fmicb.2024.1476429
- Citations
- 2
- Primary Topic
- Antifungal resistance and susceptibility
- Type
- article
- Field-Weighted Citation Impact
- 0.78
Funders
- Yunnan University