Toxicological Assessment of 2-Hydroxychalcone-Mediated Photodynamic Therapy: Comparative In Vitro and In Vivo Approaches
There was a strong correlation between the in vitro and in vivo tests, with similar toxicity results, particularly in the 3D models and <i>C. elegans</i>, where the concentration for 50% viability was approximately 100 µg/mL.
Authors
- Ana Marisa Fusco‐Almeida (ORCID: https://orcid.org/0000-0002-2115-8988)
- Letícia Ribeiro de Assis (ORCID: https://orcid.org/0000-0001-9869-8934)
- Níura Madalena Bila (ORCID: https://orcid.org/0000-0002-4236-3366)
- Luís Octávio Regasini (ORCID: https://orcid.org/0000-0001-8574-0670)
- Carolina Orlando Vaso (ORCID: https://orcid.org/0000-0002-4629-680X)
- Carla Raquel Fontana (ORCID: https://orcid.org/0000-0002-9135-3690)
- Maria José Soares Mendes‐Giannini (ORCID: https://orcid.org/0000-0002-8059-0826)
- Jenyffie Araújo Belizário
- Caroline Barcelos Costa-Orlandi
Institutions
- Eduardo Mondlane University (MZ)
- Universidade Estadual Paulista (Unesp) (BR)
Publication Details
- Journal
- Pharmaceutics
- Published
- 2024-11-26
- DOI
- https://doi.org/10.3390/pharmaceutics16121523
- Citations
- 1
- Primary Topic
- Photodynamic Therapy Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.42