Effect of elamipretide and methylprednisolone treatment on optic nerve, retina and brain damage in a methanol poisoning model: biochemical and histopathological evaluation
Combined elamipretide and methylprednisolone treatment improved optic nerve and retinal degeneration, reduced neuronal degeneration in the caudatoputamen, decreased oxidative stress and lipid peroxidation, and reduced apoptosis in the retina and caudatoputamen.
Authors
- Vildan Özer (ORCID: https://orcid.org/0000-0002-2514-5674)
- Renad Mammadov (ORCID: https://orcid.org/0000-0002-5785-1960)
- Ali Kulaber (ORCID: https://orcid.org/0000-0003-0874-8825)
- Bahadır Süleyman (ORCID: https://orcid.org/0000-0001-5795-3177)
- Engin Yeni̇lmez (ORCID: https://orcid.org/0000-0002-0755-4394)
- Ozlem Bulbul (ORCID: https://orcid.org/0000-0002-1719-1646)
- Yunus Karaca (ORCID: https://orcid.org/0000-0002-0947-0565)
- Hüseyin Yaman (ORCID: https://orcid.org/0000-0003-4440-3912)
- Aynur Şahin (ORCID: https://orcid.org/0000-0002-2679-6276)
Institutions
- Karadeniz Technical University (TR)
- Erzincan Binali Yıldırım University (TR)
- Sağlık Bilimleri Üniversitesi (TR)
- İstanbul Başakşehir Çam ve Sakura Şehir Hastanesi
- University of Health Sciences Antigua (AG)
Publication Details
- Journal
- Cutaneous and Ocular Toxicology
- Published
- 2024-11-27
- DOI
- https://doi.org/10.1080/15569527.2024.2430241
- Primary Topic
- Poisoning and overdose treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00