Impact of Antibiotics and Chronic Medications on Efficacy of Immune Checkpoint Inhibitors in Patients With Hepatocellular Carcinoma
The use of antibiotics may diminish ICI efficacy in patients with aHCC of viral hepatitis etiology, while the use of metformin, statins, beta-blockers, NSAIDs, and aspirin is not associated with significant clinical outcomes.
Authors
- Jack Jie En Tan
- Kennedy Yao Yi Ng (ORCID: https://orcid.org/0000-0001-6630-3803)
- Han Chong Toh (ORCID: https://orcid.org/0000-0003-0642-3453)
- Su Pin Choo (ORCID: https://orcid.org/0000-0002-8925-3922)
- Sze Huey Tan (ORCID: https://orcid.org/0000-0002-3089-7379)
- Suat Ying Lee (ORCID: https://orcid.org/0000-0003-3054-0174)
- Ailica Wan Xin Lee
- Lawrence Wen Jun Wong
- Joycelyn Jie Xin Lee (ORCID: https://orcid.org/0000-0002-1070-6125)
- Albert E. Teo (ORCID: https://orcid.org/0009-0005-9286-8054)
- David Tai (ORCID: https://orcid.org/0000-0002-2612-0065)
- Andrea Jing Shi Ang
- Desiree Shu Hui Tay
Institutions
- National University of Singapore (SG)
- Singapore General Hospital (SG)
- KK Women's and Children's Hospital (SG)
- Duke-NUS Medical School (SG)
- National Cancer Centre Singapore (SG)
Publication Details
- Journal
- Asia-Pacific Journal of Clinical Oncology
- Published
- 2024-11-27
- DOI
- https://doi.org/10.1111/ajco.14139
- Citations
- 4
- Primary Topic
- Hepatocellular Carcinoma Treatment and Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 1.48