Outcomes of Hematopoietic Stem Cell Transplantation in Patients With Thalassemia Major: How Do Anti‐HLA Antibodies Impact?
Anti-HLA antibodies primarily delayed platelet engraftment in TM patients and increased the erythrocyte and thrombocyte transfusion requirements. Although PRA positivity was more common in patients with primary graft failure or who died, there was no statistically significant impact of PRA positivity on chimerism, acute or chronic GVHD, viral activation, or mortality rates.
Authors
- Gürcan Dikme (ORCID: https://orcid.org/0000-0002-2286-9108)
- Özlem Öner (ORCID: https://orcid.org/0000-0001-6171-2114)
- Melek Erdem (ORCID: https://orcid.org/0000-0002-1000-7201)
- Başak Adaklı Aksoy (ORCID: https://orcid.org/0000-0001-8338-2101)
- Gizem Zengin Ersoy (ORCID: https://orcid.org/0000-0002-8968-9849)
- Selime Aydoğdu (ORCID: https://orcid.org/0000-0003-3380-3080)
- Ceyhun Bozkurt (ORCID: https://orcid.org/0000-0001-6771-9894)
- Tunç Fışgın (ORCID: https://orcid.org/0000-0003-4467-9935)
- Lokman Karataş (ORCID: https://orcid.org/0000-0003-1635-9651)
Institutions
- Istanbul Aydın University (TR)
- Ümraniye Eğitim ve Araştırma Hastanesi (TR)
- Istinye University (TR)
- Altınbaş University (TR)
Publication Details
- Journal
- Clinical Transplantation
- Published
- 2024-11-27
- DOI
- https://doi.org/10.1111/ctr.70035
- Primary Topic
- Hematopoietic Stem Cell Transplantation
- Type
- article
- Field-Weighted Citation Impact
- 0.00