Kidney function mediates the effects of four per-and polyfluoroalkyl substances (PFAS) on atherosclerotic cardiovascular disease

Exposure levels of four PFAS do not significantly increase the risk of ASCVD unless they reach a certain threshold, and the decline in kidney function exerts a significant mediating effect in the relationship between four PFAS exposure and ASCVD risk.

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Publication Details

Journal
Ecotoxicology and Environmental Safety
Published
2024-11-27
DOI
https://doi.org/10.1016/j.ecoenv.2024.117395
Citations
10
Primary Topic
Per- and polyfluoroalkyl substances research
Type
article
Field-Weighted Citation Impact
2.50
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article

Kidney function mediates the effects of four per-and polyfluoroalkyl substances (PFAS) on atherosclerotic cardiovascular disease

Ziyue Yin, Zhengqi Wei, Keke Wei, Lei Zhang et al.
10 citations
Ecotoxicology and Environmental Safety
Per- and polyfluoroalkyl substances research
2.50
article

Kidney function mediates the effects of four per-and polyfluoroalkyl substances (PFAS) on atherosclerotic cardiovascular disease

Ziyue Yin, Zhengqi Wei, Keke Wei, Lei Zhang, Ming Yang, Ming Ying, Na Wang
article en
10 citations

Abstract

Exposure levels of four PFAS do not significantly increase the risk of ASCVD unless they reach a certain threshold, and the decline in kidney function exerts a significant mediating effect in the relationship between four PFAS exposure and ASCVD risk.

Ecotoxicology and Environmental SafetyVol. 288
Shandong University (CN), Guilin Medical University (CN), Shandong Maternal and Child Health Hospital (CN)
Good health and well-being
Openalex Percentile: Top 11%
Per- and polyfluoroalkyl substances research
2.50
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