Challenges in renally eliminated medication use: Evaluating cystatin C and serum creatinine <scp>eGFR</scp> discordance
Substantial eGFR discordance between eGFR<sub>CysC</sub> and eGFR<sub>Cr</sub> was observed in hospitalized patients, which directly affects the dosing of renally eliminated medications. Further research is needed to optimize the pharmacotherapy of renally eliminated medications with discordant GFR assessments to improve medication safety and effectiveness.
Authors
- Sandra L. Kane‐Gill (ORCID: https://orcid.org/0000-0001-7523-4846)
- Hilary R. Teaford (ORCID: https://orcid.org/0000-0002-2120-7380)
- Patrick M. Wieruszewski (ORCID: https://orcid.org/0000-0002-5871-5186)
- Jaleh Zand (ORCID: https://orcid.org/0009-0001-9934-385X)
- Andrew D. Rule (ORCID: https://orcid.org/0000-0003-0338-7784)
- Jason N. Barreto (ORCID: https://orcid.org/0000-0003-2146-5766)
- Erin F. Barreto (ORCID: https://orcid.org/0000-0002-0996-1487)
- Kristin Cole (ORCID: https://orcid.org/0000-0002-8783-0191)
- Ellen Kelly (ORCID: https://orcid.org/0000-0001-5701-5156)
- Shivam Damani
- KIANOUSH B KASHANI (ORCID: https://orcid.org/0000-0003-2184-3683)
- Brandy N. Hernandez
Institutions
- Mayo Clinic (US)
- University of Pittsburgh (US)
- WinnMed (US)
- Mayo Clinic in Florida (US)
Publication Details
- Journal
- Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy
- Published
- 2024-11-27
- DOI
- https://doi.org/10.1002/phar.4627
- Citations
- 4
- Primary Topic
- Chronic Kidney Disease and Diabetes
- Type
- article
- Field-Weighted Citation Impact
- 1.36
Funders
- National Institutes of Health
- National Institute of Allergy and Infectious Diseases