Integrating metabolomics and network pharmacology to investigate Da-Chai-Hu Decoction prevents kidney injury in diabetic mice
The results indicate that DCHD treats DN through the inhibition of the AGEs/RAGE/AKT pathway and by regulating metabolic profiles.
Authors
- Zhu-Jun Zhong
- Chao‐Fan Deng
- Dan Tang (ORCID: https://orcid.org/0000-0003-0364-2220)
- Pengfei Chen (ORCID: https://orcid.org/0000-0003-1484-2850)
- Xiaomei Chen (ORCID: https://orcid.org/0000-0001-5099-2990)
- Gui‐Zhong Xin (ORCID: https://orcid.org/0000-0002-2804-8597)
- Xue Wang (ORCID: https://orcid.org/0009-0002-1823-4086)
Institutions
- Guangzhou University of Chinese Medicine (CN)
- China Pharmaceutical University (CN)
- Guangdong Pharmaceutical University (CN)
- State Administration of Traditional Chinese Medicine of the People's Republic of China (CN)
Publication Details
- Journal
- Journal of Ethnopharmacology
- Published
- 2024-11-27
- DOI
- https://doi.org/10.1016/j.jep.2024.119158
- Citations
- 8
- Primary Topic
- Metabolomics and Mass Spectrometry Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.87