Mild Aerobic Oxidation of Secondary Alcohols with Water Tolerant Cu(I) Catalyst
Green, aerobic oxidation of secondary alcohols to ketones poses a significant synthetic challenge. To address this, we have developed a highly active (DPA)CuI/ABNO catalyst system capable of aerobically oxidizing a wide range of secondary alcohols, including benzylic and aliphatic derivatives, yielding the corresponding ketones with high yields. The unique feature of this Cu(I) catalyst is its high stability, even in the presence of water. We also prepared CuI from waste copper sources to enhance the system's sustainability.
Authors
- Emi Lagerspets (ORCID: https://orcid.org/0000-0003-2338-8389)
- Timo Repo (ORCID: https://orcid.org/0000-0002-3116-6199)
- Joseph Install (ORCID: https://orcid.org/0000-0003-1377-8711)
- Anže Zupanc (ORCID: https://orcid.org/0000-0002-3697-7839)
- Aleksi Eronen (ORCID: https://orcid.org/0000-0002-8668-4137)
- Faranak Heshmatnia
Institutions
- University of Helsinki (FI)
- University of Ljubljana (SI)
- Helsinki Institute of Physics (FI)
- Aalto University (FI)
Publication Details
- Journal
- ChemSusChem
- Published
- 2024-11-27
- DOI
- https://doi.org/10.1002/cssc.202402236
- Citations
- 3
- Primary Topic
- Oxidative Organic Chemistry Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.75
Funders
- Helsingin Yliopisto
- Magnus Ehrnroothin Säätiö