Pediatric Renal Cell Carcinoma (pRCC) Subpopulation Environmental Differentials in Survival Disadvantage of Black/African American Children in the United States: Large-Cohort Evidence
pRCC indicates an increased trend in males and age at diagnosis between 10 and 14, as well as a survival disadvantage among black/AA children, compared with their white counterparts. Additionally, urbanity significantly influences the racial differences in survival. These data are suggestive of the conjoined effect of environment and race in pRCC survival, indicative of further assessment of gene-environment interaction (epigenomics) in incidence, mortality, and survival in pRCC.
Authors
- Michael Enwere (ORCID: https://orcid.org/0000-0002-3797-2327)
- Robert C. Mason (ORCID: https://orcid.org/0000-0002-5267-2189)
- Phatsimo Masire
- Maura Poleon (ORCID: https://orcid.org/0000-0002-5482-0309)
- Arieanna Eaton (ORCID: https://orcid.org/0000-0003-2872-0395)
- J. Sanders William
- Laurens Holmes (ORCID: https://orcid.org/0000-0003-3210-6806)
- Mackenzie Holmes
Institutions
- Delaware State University (US)
- Thomas Jefferson University (US)
- Alma College (US)
- Medical College of Wisconsin (US)
- Center for Health and Gender Equity (US)
- University of Delaware (US)
- Wesley College (US)
- Texas A&M University (US)
Publication Details
- Journal
- Cancers
- Published
- 2024-11-27
- DOI
- https://doi.org/10.3390/cancers16233975
- Primary Topic
- Renal and related cancers
- Type
- article
- Field-Weighted Citation Impact
- 0.00