Ranked Importance of Visual Function Outcome Measures in Choroideremia Clinical Trials

Clinical trials in choroideremia for early and mid-stage disease would be justified in moving away from using standard BCVA as a clinical trial outcome measure as we have shown its sensitivity to be relatively low compared to microperimetry. We have also demonstrated how functional measures rank in terms of importance.

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Institutions

Publication Details

Journal
Investigative Ophthalmology & Visual Science
Published
2024-11-27
DOI
https://doi.org/10.1167/iovs.65.13.58
Citations
2
Primary Topic
Retinal Diseases and Treatments
Type
article
Field-Weighted Citation Impact
1.08

Funders

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article

Ranked Importance of Visual Function Outcome Measures in Choroideremia Clinical Trials

Amandeep S. Josan, Laura J. Taylor, Robert E. MacLaren, Jasmina Cehajic‐Kapetanovic et al.
2 citations
Investigative Ophthalmology & Visual Science
Retinal Diseases and Treatments
1.08
article

Ranked Importance of Visual Function Outcome Measures in Choroideremia Clinical Trials

Amandeep S. Josan, Laura J. Taylor, Robert E. MacLaren, Jasmina Cehajic‐Kapetanovic, Kanmin Xue
article en
2 citations

Abstract

Clinical trials in choroideremia for early and mid-stage disease would be justified in moving away from using standard BCVA as a clinical trial outcome measure as we have shown its sensitivity to be relatively low compared to microperimetry. We have also demonstrated how functional measures rank in terms of importance.

Investigative Ophthalmology & Visual ScienceVol. 65(13)
University of Oxford (GB), Oxford BioMedica (United Kingdom) (GB), Oxford University Hospitals NHS Trust (GB)
National Institute for Health and Care Research
Openalex Percentile: Top 21%
Retinal Diseases and Treatments
1.08
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