Silver Nanoparticles from Duddingtonia flagrans: Evaluation of Potential Ovicidal Activity on Toxocara canis Eggs
The filtrate of the nematophagous fungus <i>Duddingtonia flagrans</i> produces silver nanoparticles (AgNPs) with nematicidal potential. However, there are currently no reports of its activity against <i>Toxocara canis</i> eggs. The aim of this study was to investigate the potential ovicidal activity of AgNPs-<i>D. flagrans</i> on <i>T. canis</i> eggs. <i>T. canis</i> eggs were obtained from the dissection of the uterus of adult female nematodes. After the biosynthesis of AgNPs, two experimental assays (A and B) were performed. In assay A, the ovicidal activity of AgNPs on eggs was evaluated after 15 and 30 days of interaction. In assay B, the inhibition (development) of the eggs was measured after 30 days of interaction. The results of assay A showed that the AgNPs destroyed an average of 47% of the eggs tested by the end of the experiment, causing significant structural damage. In assay B, an inhibition rate of 88% was observed at the end of 30 days. The results of the ovicidal activity of AgNP-<i>D. flagrans</i> were promising and indicate the potential for future studies on these biomolecules with ovicidal properties.
Authors
- Fernando Luiz Tobias (ORCID: https://orcid.org/0000-0003-3841-480X)
- Jackson Víctor de Araújo (ORCID: https://orcid.org/0000-0001-7367-4071)
- Fábio Ribeiro Braga (ORCID: https://orcid.org/0000-0003-2942-5785)
- João Pedro Barbosa de Assis (ORCID: https://orcid.org/0000-0002-0989-4755)
- Carolina Magri Ferraz (ORCID: https://orcid.org/0000-0003-0390-3240)
- Laryssa Pinheiro Costa Silva
- Filippe Elias de Freitas Soares (ORCID: https://orcid.org/0000-0001-7280-9536)
- Hélio Langoni (ORCID: https://orcid.org/0000-0001-5127-0762)
- Vinícius Longo Ribeiro Vilela (ORCID: https://orcid.org/0000-0001-9891-7842)
- Vinícius Bastos Salles Segantine
- Gabriel Augusto Marques Rossi (ORCID: https://orcid.org/0000-0001-7967-7628)
- Lara Coslop Comério
- Lara De Nadai Rodrigues Bezerra
Institutions
- Universidade Federal de Lavras (BR)
- Universidade Federal de Viçosa (BR)
- Instituto Federal de Educação Ciência e Tecnologia da Paraíba (BR)
- Universidade Vila Velha (BR)
Publication Details
- Journal
- Pathogens
- Published
- 2024-11-27
- DOI
- https://doi.org/10.3390/pathogens13121043
- Citations
- 2
- Primary Topic
- Nanoparticles: synthesis and applications
- Type
- article
- Field-Weighted Citation Impact
- 0.23
Funders
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Fundação de Amparo à Pesquisa do Estado de Minas Gerais
- Fundação de Amparo à Pesquisa e Inovação do Espírito Santo