Analysis of the Sensitivity and Specificity of Histopathological Findings for Diagnosing Lupus Nephritis
The combination of mesangial proliferation, subendothelial deposits, C1q staining ≥1+, dominant IgG, and ≥4 positive immunofluorescence elements offer good accuracy for diagnosing renal involvement in SLE in a large Latin American population. In the absence of pathognomonic features, combined criteria are valuable diagnostic tools, particularly when other SLE criteria are lacking.
Authors
- Estrela Neto (ORCID: https://orcid.org/0000-0003-2334-2292)
- Maria Brandão Tavares (ORCID: https://orcid.org/0000-0002-7549-0513)
- Washington L. C. dos‐Santos (ORCID: https://orcid.org/0000-0002-5075-1254)
- Ana Melo (ORCID: https://orcid.org/0000-0002-6308-9343)
- Denise Maria Avancini Costa Malheiros (ORCID: https://orcid.org/0000-0002-0409-816X)
- Luís Yu (ORCID: https://orcid.org/0000-0001-9102-0063)
Institutions
- Universidade Federal da Bahia (BR)
- Universidade de São Paulo (BR)
- Complexo Hospitalar Universitário Professor Edgard Santos (BR)
- Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (BR)
- Hospital Ana Nery (BR)
- Fundação Oswaldo Cruz (BR)
Publication Details
- Journal
- Diagnostics
- Published
- 2024-11-27
- DOI
- https://doi.org/10.3390/diagnostics14232681
- Citations
- 1
- Primary Topic
- Systemic Lupus Erythematosus Research
- Type
- article
- Field-Weighted Citation Impact
- 0.47