Prognostic relevance of Exercise Pulmonary Hypertension: Results of the multi-center PEX-NET Clinical Research Collaboration
The mPAP/CO slope is a robust and independent predictor of prognosis in patients with normal or mildly elevated resting PAP that provides prognostic information beyond resting haemodynamics and appears suitable to define exercise PH.
Authors
- Joan Albert Barberà (ORCID: https://orcid.org/0000-0003-1469-4990)
- Ralf Ewert (ORCID: https://orcid.org/0000-0002-6746-9925)
- Silvia Ulrich (ORCID: https://orcid.org/0000-0002-5250-5022)
- Alexander Avian (ORCID: https://orcid.org/0000-0003-1084-5763)
- Anton Vonk Noordegraaf (ORCID: https://orcid.org/0000-0002-4057-758X)
- Gregory D. Lewis (ORCID: https://orcid.org/0000-0001-8108-8240)
- Mads J. Andersen (ORCID: https://orcid.org/0000-0002-9320-8227)
- Marcin Kurzyna (ORCID: https://orcid.org/0000-0002-6746-469X)
- Stéphanie Saxer (ORCID: https://orcid.org/0000-0002-3278-6277)
- Steven Hsu (ORCID: https://orcid.org/0000-0002-8384-2638)
- Bradley A. Maron (ORCID: https://orcid.org/0000-0002-6784-764X)
- Claudia Baratto (ORCID: https://orcid.org/0000-0003-3472-4851)
- Stephan Rosenkranz (ORCID: https://orcid.org/0000-0001-6237-1470)
- Simon Herkenrath (ORCID: https://orcid.org/0000-0002-5940-4443)
- Brian A. Houston (ORCID: https://orcid.org/0000-0001-6188-8072)
- Alexander Heine (ORCID: https://orcid.org/0000-0002-8416-8374)
- Susanna Mak (ORCID: https://orcid.org/0000-0003-2193-602X)
- Laurent Savale (ORCID: https://orcid.org/0000-0002-6862-8975)
- Rudolf K.F. Oliveira (ORCID: https://orcid.org/0000-0002-2252-8119)
- Krzysztof Kasperowicz
- Nazzareno Galiè (ORCID: https://orcid.org/0000-0003-4271-8670)
- Robin Condliffe (ORCID: https://orcid.org/0000-0002-3492-4143)
- Colm McCabe (ORCID: https://orcid.org/0000-0002-0392-8838)
- Horst Olschewski (ORCID: https://orcid.org/0000-0002-2834-7466)
- Michele D’Alto (ORCID: https://orcid.org/0000-0001-5729-1038)
- Khodr Tello (ORCID: https://orcid.org/0000-0002-5557-623X)
- Marc Humbert (ORCID: https://orcid.org/0000-0003-0703-2892)
- Rogério Souza (ORCID: https://orcid.org/0000-0003-2789-9143)
- Ekkehard Grünig (ORCID: https://orcid.org/0000-0001-7318-3918)
- Benjamin Egenlauf (ORCID: https://orcid.org/0000-0003-2466-1420)
- Rajeev Kumar Malhotra (ORCID: https://orcid.org/0000-0003-0120-4630)
- Gábor Kovács (ORCID: https://orcid.org/0000-0003-3709-2183)
- David Systrom
- Isabel Blanco (ORCID: https://orcid.org/0000-0002-8584-6691)
- Philippe Hervé (ORCID: https://orcid.org/0000-0002-8731-0014)
- Ryan J. Tedford
Institutions
- University of Maryland, Baltimore (US)
- Brigham and Women's Hospital (US)
- Harvard University (US)
- Johns Hopkins University (US)
- Medical University of South Carolina (US)
- Inserm (FR)
- Universidade de São Paulo (BR)
- University of Cologne (DE)
- University of Toronto (CA)
- University of Campania "Luigi Vanvitelli" (IT)
- Justus-Liebig-Universität Gießen (DE)
- Medical University of Graz (AT)
- University of Zurich (CH)
- Aarhus University (DK)
- Heidelberg University (DE)
- Université Paris-Saclay (FR)
- Johns Hopkins Medicine (US)
- Foundation for the National Institutes of Health (US)
- Universität Greifswald (DE)
- Massachusetts General Hospital (US)
- Ludwig Boltzmann Institute for Lung Vascular Research (AT)
- Royal Brompton Hospital (GB)
- Centre for Biomedical Network Research on Rare Diseases (ES)
- Hospital Clínic de Barcelona (ES)
- IRCCS Istituto Auxologico Italiano (IT)
- Ospedale Monaldi (IT)
- Amsterdam University Medical Centers (NL)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Consorci Institut D'Investigacions Biomediques August Pi I Sunyer (ES)
- Bicêtre Hospital (FR)
- Medical Research Network (US)
- Imperial College London (GB)
- University of Baltimore (US)
- Universitat de Barcelona (ES)
- Universidade Federal de São Paulo (BR)
- University of Sheffield (GB)
- University of Bologna (IT)
Publication Details
- Journal
- European Respiratory Journal
- Published
- 2024-11-27
- DOI
- https://doi.org/10.1183/13993003.00698-2024
- Citations
- 21
- Primary Topic
- Pulmonary Hypertension Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 8.80
Funders
- Eli Lilly and Company
- Pfizer
- AstraZeneca
- Heart and Stroke Foundation of Canada
- Boston Scientific Corporation
- European Respiratory Society
- Regeneron Pharmaceuticals
- Abiomed
- Imperial College London
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Novo Nordisk
- Vrije Universiteit Brussel
- Karl-Franzens-Universität Graz
- Medizinische Universität Graz
- Grupo Ferrer Internacional, S.A
- National Institutes of Health
- Actelion Pharmaceuticals
- Cilag