A Versatile, Low-Cost Modular Microfluidic System to Prepare Poly(Lactic-co-Glycolic Acid) Nanoparticles With Encapsulated Protein
A cheap and easily adjustable modular microfluidic system was developed to prepare PLGA nanoparticles with highly reproducible particle diameters that can effectively be loaded with proteins for drug and vaccine delivery.
Authors
- Tom H. M. Ottenhoff (ORCID: https://orcid.org/0000-0003-3706-3403)
- Koen van der Maaden (ORCID: https://orcid.org/0000-0003-0682-2403)
- Wim Jiskoot (ORCID: https://orcid.org/0000-0002-1012-3456)
- Malene Aaby Neustrup
- Joke A. Bouwstra (ORCID: https://orcid.org/0000-0002-7123-6868)
Institutions
- Leiden University (NL)
- Leiden University Medical Center (NL)
- Centre for Human Drug Research (NL)
Publication Details
- Journal
- Pharmaceutical Research
- Published
- 2024-11-27
- DOI
- https://doi.org/10.1007/s11095-024-03792-1
- Citations
- 3
- Primary Topic
- Nanoparticle-Based Drug Delivery
- Type
- article
- Field-Weighted Citation Impact
- 0.52
Funders
- Nederlandse Organisatie voor Wetenschappelijk Onderzoek