Chondroprotective functions of neutrophil-derived extracellular vesicles by promoting the production of secreted frizzled-related protein 5 in cartilage
The current study emphasizes the potential therapeutic application of neutrophils in OA and provides new knowledge on the molecular mechanisms underlying their function.
Authors
- Tomohiro Onodera
- Tatsuya Nagano (ORCID: https://orcid.org/0000-0003-0790-5139)
- Liyile Chen (ORCID: https://orcid.org/0000-0002-8004-5246)
- Mohamad Alaa Terkawi (ORCID: https://orcid.org/0000-0002-5481-8516)
- Junki Shiota
- Taku Ebata
- Keita Kitahara
- Norimasa Iwasaki (ORCID: https://orcid.org/0000-0002-5496-4046)
- Yuki Ogawa (ORCID: https://orcid.org/0000-0001-5798-7895)
- Ken Kadoya (ORCID: https://orcid.org/0000-0001-5432-3866)
- Tsutomu Endo (ORCID: https://orcid.org/0000-0002-2998-2242)
- Yoshio Nishida
- Kentaro Homan (ORCID: https://orcid.org/0000-0002-0288-7691)
- Hend Alhasan
- Tomohiro Shimizu
- Taiki Tokuhiro
- Taichi E. Takasuka (ORCID: https://orcid.org/0000-0002-4413-2924)
- Daisuke Takahashi (ORCID: https://orcid.org/0000-0003-4740-3643)
- Tsuyoshi Asano
Institutions
- Hokkaido University (JP)
Publication Details
- Journal
- Cell Communication and Signaling
- Published
- 2024-11-27
- DOI
- https://doi.org/10.1186/s12964-024-01953-8
- Citations
- 5
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 2.35
Funders
- Japan Agency for Medical Research and Development
- Japan Society for the Promotion of Science
- Moonshot Research and Development Program