Polygenic Score for Clinicopathologic Features and Survival Outcomes in Papillary Thyroid Carcinoma
Findings of this cohort study suggest that patients with a higher germline risk of PTC, as estimated by PGS, present with more aggressive clinicopathologic features. These results contribute to the current understanding of inherited risk in PTC and how germline variants could potentially contribute to disease presentation and clinical outcomes.
Authors
- Mark Zafereo (ORCID: https://orcid.org/0000-0001-7918-9739)
- Jennifer Wang (ORCID: https://orcid.org/0000-0002-0807-3832)
- Maitrayee Goswami
- Guibin Zheng (ORCID: https://orcid.org/0000-0002-9087-6502)
- Steven I. Sherman (ORCID: https://orcid.org/0000-0002-3079-5153)
- Guojun Li (ORCID: https://orcid.org/0000-0001-9505-1502)
- Sophie H. Li (ORCID: https://orcid.org/0000-0002-3099-9906)
- Erich M. Sturgis (ORCID: https://orcid.org/0000-0002-1069-4822)
- Li Xu
Institutions
- The University of Texas MD Anderson Cancer Center (US)
- Baylor College of Medicine (US)
Publication Details
- Journal
- JAMA Otolaryngology–Head & Neck Surgery
- Published
- 2024-11-27
- DOI
- https://doi.org/10.1001/jamaoto.2024.3963
- Citations
- 1
- Primary Topic
- Thyroid Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.36