Next-Generation Sequencing for HLA Genotype Screening and Matching to HLA-Restricted Therapies

This case series evaluates whether human leukocyte antigen ( HLA ) genotype could be inferred from standard next-generation sequencing, comparing concordance with confirmatory whole-exome sequencing and assessing if this assisted in matching patients to clinical trials.

Authors

Institutions

Publication Details

Journal
JAMA Oncology
Published
2024-11-27
DOI
https://doi.org/10.1001/jamaoncol.2024.5364
Citations
3
Primary Topic
Renal Transplantation Outcomes and Treatments
Type
article
Field-Weighted Citation Impact
1.52
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Next-Generation Sequencing for HLA Genotype Screening and Matching to HLA-Restricted Therapies

Cynthia Chu, Claire F. Friedman, Kaelyn Kohlasch, Michael V. Gormally et al.
3 citations
JAMA Oncology
Renal Transplantation Outcomes and Treatments
1.52
article

Next-Generation Sequencing for HLA Genotype Screening and Matching to HLA-Restricted Therapies

Cynthia Chu, Claire F. Friedman, Kaelyn Kohlasch, Michael V. Gormally, Michael Eubank, Adam J. Schoenfeld, Anne Marie Noronha, Chrisann Kyi, Clare Wilhelm, Mark T.A. Donoghue, Nikeysha Clarke, Mark G. Kris, Alexander Noor Shoushtari, Charles M. Rudin, Ronak H. Shah, Alexander Edward Dela Cruz Drilon, David H. Aggen, Monica F. Chen, Christopher Austin Klebanoff, Amanda G. Blouin, Bryan Novak, Chaitanya Bandlamudi, Sandra P. D’Angelo, Tatiana Kee-Velez, Michael F. Berger, Kristalla Panageas, Maggie Reynolds
article en
3 citations

Abstract

This case series evaluates whether human leukocyte antigen ( HLA ) genotype could be inferred from standard next-generation sequencing, comparing concordance with confirmatory whole-exome sequencing and assessing if this assisted in matching patients to clinical trials.

JAMA OncologyVol. 11(1)
Memorial Sloan Kettering Cancer Center (US), Molecular Oncology (United States) (US)
Openalex Percentile: Top 18%
Renal Transplantation Outcomes and Treatments
1.52
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.