SENP1 Promotes Caspase-11 Inflammasome Activation and Aggravates Inflammatory Response in Murine Acute Lung Injury Induced by Lipopolysaccharide
Collectively, our findings highlight the involvement of SENP1 in caspase-11 activation and inflammatory progression in macrophages, thereby establishing a scientific foundation for the exploration of novel therapeutic strategies aimed at treating ALI.
Authors
- Wenhan Wang (ORCID: https://orcid.org/0000-0001-7178-8286)
- Chunbing Zhang (ORCID: https://orcid.org/0000-0001-5576-7821)
- Shaoyuan Zhang (ORCID: https://orcid.org/0000-0002-6187-4313)
- Mingjun Du (ORCID: https://orcid.org/0000-0001-6848-6981)
- Jianmin Gu (ORCID: https://orcid.org/0000-0002-4031-8385)
- Hai Zhang (ORCID: https://orcid.org/0000-0002-8705-6351)
Institutions
- Sun Yat-sen University (CN)
- Shanghai Jiao Tong University (CN)
- Fudan University (CN)
- Renji Hospital (CN)
- Shanghai Chest Hospital (CN)
- Zhongshan Hospital (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
- Jiangsu Province Hospital (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Frontiers in Bioscience-Landmark
- Published
- 2024-11-21
- DOI
- https://doi.org/10.31083/j.fbl2911397
- Citations
- 1
- Primary Topic
- Inflammasome and immune disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.23
Funders
- Natural Science Foundation of Jiangsu Province