Sodium Iodate: Rapid and Clinically Relevant Model of AMD
The data suggest that NaIO<sub>3</sub> induces the formation of HRF in the outer retina and their abundance correlates with retinal tissue loss. The experiments in this study highlight NaIO<sub>3</sub> as a clinically relevant model of intermediate AMD that can be used to study HRF formation and to discover new treatment targets.
Authors
- Jeffrey M. Sundstrom (ORCID: https://orcid.org/0000-0003-2738-2224)
- Stephanie L. Grillo
- Jasmine Geathers (ORCID: https://orcid.org/0000-0002-5201-7854)
- Alistair J. Barber (ORCID: https://orcid.org/0000-0003-4235-2293)
- Yuanjun Zhao (ORCID: https://orcid.org/0000-0002-0438-0747)
- Han Chen (ORCID: https://orcid.org/0000-0002-5912-3692)
- Yong Du (ORCID: https://orcid.org/0009-0003-4760-5664)
- Ema Karakoleva
- Gregory P. Campbell
Institutions
- Pennsylvania State University (US)
Publication Details
- Journal
- Frontiers in Bioscience-Landmark
- Published
- 2024-11-13
- DOI
- https://doi.org/10.31083/j.fbl2911380
- Citations
- 5
- Primary Topic
- Retinal Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.69