Anterograde versus Retrograde Effects of Damage to Identified Learning and Memory Systems during Acquisition, Retention, and Re-Acquisition of an Instrumental Visual Discrimination Task: Dorsal Striatum, Perirhinal Cortex, and Hippocampus
Taken together, the results of the present experiments show that the dorsomedial striatum and the hippocampus may support performance on this instrumental task if intact during acquisition but is not required for acquisition of a new problem. The implications of this pattern of results for our understanding of the organization of learning and memory in mammals is discussed.
Authors
- Robert J. Sutherland (ORCID: https://orcid.org/0000-0002-2539-4312)
- Robert J. McDonald (ORCID: https://orcid.org/0000-0002-7750-7155)
- Fraser T. Sparks (ORCID: https://orcid.org/0000-0002-4716-5246)
- Hugo Lehmann
- Joelle Kopp
- Erin L. Zelinski (ORCID: https://orcid.org/0000-0001-9188-9631)
- Nancy S. Hong
Institutions
- University of Lethbridge (CA)
- Regeneron (United States) (US)
- Trent University (CA)
Publication Details
- Journal
- Journal of Integrative Neuroscience
- Published
- 2024-11-18
- DOI
- https://doi.org/10.31083/j.jin2311205
- Citations
- 1
- Primary Topic
- Memory and Neural Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.34
Funders
- University of Lethbridge
- Natural Sciences and Engineering Research Council of Canada