HMGB1 Modulates Macrophage Metabolism and Polarization in Ulcerative Colitis by Inhibiting Cpt1a Expression
HMGB1 modulates macrophage metabolism in UC by inhibiting Cpt1a expression, leading to increased M1 polarization. This provides a theoretical basis for the clinical application of HMGB1 inhibitors in the treatment of UC.
Authors
- Linfei Luo
- Zhengqiang Wu
- Fenfen Wang (ORCID: https://orcid.org/0000-0003-1095-8127)
- Fan Li (ORCID: https://orcid.org/0000-0001-8582-4911)
- Lijun Wan (ORCID: https://orcid.org/0000-0002-0932-0938)
- Zhili Wen (ORCID: https://orcid.org/0000-0002-8263-1644)
Institutions
- Nanchang University (CN)
- Second Affiliated Hospital of Nanchang University (CN)
Publication Details
- Journal
- Frontiers in Bioscience-Landmark
- Published
- 2024-11-19
- DOI
- https://doi.org/10.31083/j.fbl2911387
- Citations
- 7
- Primary Topic
- Immune cells in cancer
- Type
- article
- Field-Weighted Citation Impact
- 1.68