Comprehensive Assessment of Initial Adaptation of Extended-Spectrum β-Lactamase–Positive ST131 <i>Escherichia coli</i> to Carbapenem Exposure
ESBL gene amplification is a conserved response to initial carbapenem exposure, especially within the high-risk ST131 C2/H30Rx subclade. Targeting such amplification could assist with mitigating carbapenem resistance development.
Authors
- William C. Shropshire (ORCID: https://orcid.org/0000-0001-8556-3248)
- Selvalakshmi Selvaraj Anand
- César A. Arias (ORCID: https://orcid.org/0000-0001-9054-9774)
- Anna Konovalova (ORCID: https://orcid.org/0000-0002-2238-8849)
- Seokju Seo (ORCID: https://orcid.org/0000-0003-1699-6271)
- Awdhesh Kalia (ORCID: https://orcid.org/0000-0001-5365-1702)
- Xinhao Song (ORCID: https://orcid.org/0009-0009-4776-2428)
- Yousif Shamoo (ORCID: https://orcid.org/0000-0001-9241-8962)
- Samuel A. Shelburne (ORCID: https://orcid.org/0000-0001-9721-263X)
- Jordan Bremer
- An Q Dinh (ORCID: https://orcid.org/0000-0002-2965-9269)
- Micah M. Bhatti (ORCID: https://orcid.org/0000-0001-5857-5825)
- Susana Rodríguez (ORCID: https://orcid.org/0000-0002-7136-3728)
Institutions
- Houston Methodist (US)
- The University of Texas MD Anderson Cancer Center (US)
- Cornell University (US)
- Methodist Hospital (US)
- Rice University (US)
- The University of Texas Health Science Center at Houston (US)
Publication Details
- Journal
- The Journal of Infectious Diseases
- Published
- 2024-11-27
- DOI
- https://doi.org/10.1093/infdis/jiae587
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health
- University of Texas MD Anderson Cancer Center
- National Institute of Allergy and Infectious Diseases