[Mechanism of Tongfu Lifei decoction inhibiting the programmed death-1/programmed death-ligand 1 signaling pathway in THP-1 cells by regulating microRNA-146a].
TFL regulates the expression of miR-146a to inhibit the PD-1/PD-L1 signaling pathway in THP-1 cells, regulates the immune barrier of sepsis induced in cell inflammation model in vitro, and thus protects LPS induced THP-1 cells.
Authors
- Bo Lyu (ORCID: https://orcid.org/0000-0002-2744-730X)
- Ruifeng Huang (ORCID: https://orcid.org/0000-0002-5429-517X)
- Lipeng Han (ORCID: https://orcid.org/0000-0001-9077-922X)
- Lan Li (ORCID: https://orcid.org/0000-0003-3858-3988)
- Xiahui Zhou
Institutions
- Guizhou University (CN)
- Affiliated Hospital of Guizhou Medical University (CN)
Publication Details
- Journal
- PubMed
- Published
- 2024-10-01
- DOI
- https://doi.org/10.3760/cma.j.cn121430-20240229-00180
- Primary Topic
- Traditional Chinese Medicine Analysis
- Type
- article