Application of MAP-MRI Diffusion Model in Preoperative Brain Development in Infants with Congenital Heart Disease

Motivation: Non-invasive quantitative methods to assess the brain development of children with congenital heart disease (CHD) has been a hot topic . Goal(s): The main focus of this study is to investigate how MAP-MRI can be used to assess preoperative brain development in children with CHD. Approach: In this study, quantitative and correlational analyses of preoperative brain development in CHD children were performed using the multi-parameter indicators of the MAP-MRI diffusion model. Results: The results show that children with CHD exhibit cerebral microstructural abnormalities preoperatively, and MAP-MRI parameter indicators can be used for early prediction of preoperative neurodevelopment in CHD children. Impact: MAP-MRI parameter indicators can serve as imaging reference values for preoperative brain development in children with CHD, aiding clinical professionals in focusing on the neurodevelopment of these patients while treating their CHD.